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Gene: SRP54 (signal recognition particle 54) Homo sapiens
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Symbol: SRP54
Name: signal recognition particle 54
Description: Exhibits several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and purine ribonucleoside binding activity. Contributes to GTPase activity. Involved in protein targeting to ER and response to drug. Localizes to the cytosol; nucleus; and signal recognition particle, endoplasmic reticulum targeting; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; benzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: signal recognition particle 54 kDa protein; signal recognition particle 54kD; signal recognition particle 54kDa
Orthologs:
Mus musculus (house mouse) : Srp54a (signal recognition particle 54A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srp54a (signal recognition particle 54A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srp54 (signal recognition particle 54)
Pan paniscus (bonobo/pygmy chimpanzee) : SRP54 (signal recognition particle 54)
Canis lupus familiaris (dog) : SRP54 (signal recognition particle 54)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srp54 (signal recognition particle 54)
Sus scrofa (pig) : SRP54 (signal recognition particle 54)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381434,982,898 - 35,029,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371435,451,901 - 35,498,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,521,982 - 34,568,519 (+)NCBINCBI36hg18NCBI36
Build 341434,521,981 - 34,568,517NCBI
Celera1415,315,912 - 15,362,600 (+)NCBI
Cytogenetic Map14q13.2NCBI
HuRef1415,564,659 - 15,611,702 (+)NCBIHuRef
CHM1_11435,450,690 - 35,497,725 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SRP54
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350478
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.