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Gene: SCN1B (sodium voltage-gated channel beta subunit 1) Homo sapiens
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Symbol: SCN1B
Name: sodium voltage-gated channel beta subunit 1
CRRD ID: 1350483
Description: Exhibits sodium channel regulator activity and voltage-gated sodium channel activity involved in Purkinje myocyte action potential. Involved in several processes, including cardiac conduction; regulation of atrial cardiac muscle cell membrane depolarization; and regulation of sodium ion transport. Localizes to voltage-gated sodium channel complex. Implicated in Brugada syndrome 5; early infantile epileptic encephalopathy 52; familial atrial fibrillation; and generalized epilepsy with febrile seizures plus 1.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB13; BRGDA5; DEE52; EIEE52; GEFSP1; sodium channel beta-1 subunit; sodium channel subunit beta-1; sodium channel, voltage gated, type I beta subunit; sodium channel, voltage-gated, type I, beta; sodium channel, voltage-gated, type I, beta subunit
Orthologs:
Mus musculus (house mouse) : Scn1b (sodium channel, voltage-gated, type I, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scn1b (sodium voltage-gated channel beta subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn1b (sodium voltage-gated channel beta subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN1B (sodium voltage-gated channel beta subunit 1)
Canis lupus familiaris (dog) : SCN1B (sodium voltage-gated channel beta subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn1b (sodium voltage-gated channel beta subunit 1)
Sus scrofa (pig) : SCN1B (sodium voltage-gated channel beta subunit 1)
Chlorocebus sabaeus (African green monkey) : SCN1B (sodium voltage-gated channel beta subunit 1)
Heterocephalus glaber (naked mole-rat) : Scn1b (sodium voltage-gated channel beta subunit 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1935,030,470 - 35,040,449 (+)EnsemblGRCh38hg38GRCh38
GRCh381935,030,470 - 35,040,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371935,521,555 - 35,531,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,213,374 - 40,223,193 (+)NCBINCBI36hg18NCBI36
Build 341940,213,373 - 40,217,014NCBI
Celera1932,237,030 - 32,244,951 (+)NCBI
Cytogenetic Map19q13.11NCBI
HuRef1932,031,550 - 32,039,386 (+)NCBIHuRef
CHM1_11935,523,533 - 35,533,294 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

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Nomenclature History
 
More on SCN1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350483
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.