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Gene: NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component) Homo sapiens
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Symbol: NSMCE1
Name: NSE1 homolog, SMC5-SMC6 complex component
Description: Exhibits protein dimerization activity and ubiquitin-protein transferase activity. Involved in positive regulation of response to DNA damage stimulus. Localizes to the Smc5-Smc6 complex and nucleoplasm; INTERACTS WITH 2-hydroxypropanoic acid; 2-methylcholine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: non-SMC element 1 homolog; non-structural maintenance of chromosomes element 1 homolog; NSE1
Orthologs:
Mus musculus (house mouse) : Nsmce1 (NSE1 homolog, SMC5-SMC6 complex component)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nsmce1 (NSE1 homolog, SMC5-SMC6 complex component)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsmce1 (NSE1 homolog, SMC5-SMC6 complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component)
Canis lupus familiaris (dog) : NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsmce1 (NSE1 homolog, SMC5-SMC6 complex component)
Sus scrofa (pig) : NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381627,224,994 - 27,268,772 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371627,236,315 - 27,280,113 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361627,143,816 - 27,187,614 (-)NCBINCBI36hg18NCBI36
Build 341627,143,826 - 27,176,376NCBI
Celera1626,014,952 - 26,058,084 (-)NCBI
Cytogenetic Map16p12.1NCBI
HuRef1625,325,212 - 25,368,754 (-)NCBIHuRef
CHM1_11628,248,021 - 28,291,832 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NSMCE1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350522
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.