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Gene: DPEP1 (dipeptidase 1) Homo sapiens
Symbol: DPEP1
Name: dipeptidase 1
Description: Exhibits several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; metallodipeptidase activity; and zinc ion binding activity. Involved in several processes, including homocysteine metabolic process; negative regulation of cell migration; and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Localizes to several cellular components, including the apical part of cell; cell junction; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dehydropeptidase-I; dipeptidase 1 (renal); hRDP; MBD1; MDP; microsomal dipeptidase; RDP; renal dipeptidase; testicular tissue protein Li 57
Mus musculus (house mouse) : Dpep1 (dipeptidase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dpep1 (dipeptidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpep1 (dipeptidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DPEP1 (dipeptidase 1)
Canis lupus familiaris (dog) : DPEP1 (dipeptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpep1 (dipeptidase 1)
Sus scrofa (pig) : DPEP1 (dipeptidase 1)
Chlorocebus sabaeus (green monkey) : DPEP1 (dipeptidase 1)
Heterocephalus glaber (naked mole-rat) : Dpep1 (dipeptidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1689,613,308 - 89,638,456 (+)Ensembl
GRCh381689,613,308 - 89,641,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371689,679,716 - 89,707,216 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,214,501 - 88,232,338 (+)NCBINCBI36hg18NCBI36
Build 341688,214,500 - 88,232,338NCBI
Celera1674,743,127 - 74,769,330 (+)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1675,374,386 - 75,400,655 (+)NCBIHuRef
CHM1_11691,091,422 - 91,116,106 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DPEP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350537
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.