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Gene: WDR45B (WD repeat domain 45B) Homo sapiens
Symbol: WDR45B
Name: WD repeat domain 45B
Description: Exhibits TSC1-TSC2 complex binding activity; phosphatidylinositol-3,5-bisphosphate binding activity; and phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly and cellular response to starvation. Localizes to the lysosome and phagophore assembly site.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NEDSBAS; WD repeat domain phosphoinositide-interacting protein 3; WD repeat protein 45-like; WD repeat-containing protein 45-like; WD repeat-containing protein 45B; WDR45-like; WDR45L; WIPI-3; WIPI3; WIPI3 long; WIPI49-like protein
Mus musculus (house mouse) : Wdr45b (WD repeat domain 45B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr45b (WD repeat domain 45B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr45b (WD repeat domain 45B)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR45B (WD repeat domain 45B)
Canis lupus familiaris (dog) : WDR45B (WD repeat domain 45B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr45b (WD repeat domain 45B)
Sus scrofa (pig) : WDR45B (WD repeat domain 45B)
Chlorocebus sabaeus (green monkey) : WDR45B (WD repeat domain 45B)
Heterocephalus glaber (naked mole-rat) : Wdr45b (WD repeat domain 45B)
more info ...
Related Pseudogenes: WDR45BP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1782,614,562 - 82,648,553 (-)Ensembl
GRCh381782,614,562 - 82,648,530 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371780,572,438 - 80,606,411 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361778,165,727 - 78,199,700 (-)NCBINCBI36hg18NCBI36
Build 341778,165,741 - 78,199,566NCBI
Celera1777,166,614 - 77,200,663 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1775,972,711 - 76,006,590 (-)NCBIHuRef
CHM1_11780,658,534 - 80,692,618 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on WDR45B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350558
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.