Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TRMT2B (tRNA methyltransferase 2 homolog B) Homo sapiens
Symbol: TRMT2B
Name: tRNA methyltransferase 2 homolog B
Description: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CXorf34; dJ341D10.3; FLJ12687; TRM2 homolog; TRM2 tRNA methyltransferase 2 homolog B; tRNA (uracil(54)-C(5))-methyltransferase homolog; tRNA (uracil-5-)-methyltransferase homolog
Mus musculus (house mouse) : Trmt2b (TRM2 tRNA methyltransferase 2B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Trmt2b (tRNA methyltransferase 2 homolog B)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TRMT2B (tRNA methyltransferase 2 homolog B)
Canis lupus familiaris (dog) : TRMT2B (tRNA methyltransferase 2 homolog B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trmt2b (tRNA methyltransferase 2 homolog B)
Sus scrofa (pig) : TRMT2B (tRNA methyltransferase 2 homolog B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X100,973,359 - 101,052,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,264,334 - 100,307,105 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,151,187 - 100,193,726 (-)NCBINCBI36hg18NCBI36
Build 34X100,070,692 - 100,113,215NCBI
CeleraX100,783,109 - 100,825,878 (-)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX90,068,401 - 90,112,076 (-)NCBIHuRef
CHM1_1X100,157,442 - 100,200,214 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRMT2B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350620
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.