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Gene: TRMT2B (tRNA methyltransferase 2 homolog B) Homo sapiens
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Symbol: TRMT2B
Name: tRNA methyltransferase 2 homolog B
Description: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CXorf34; dJ341D10.3; FLJ12687; TRM2 homolog; TRM2 tRNA methyltransferase 2 homolog B; tRNA (uracil(54)-C(5))-methyltransferase homolog; tRNA (uracil-5-)-methyltransferase homolog
Orthologs:
Mus musculus (house mouse) : Trmt2b (TRM2 tRNA methyltransferase 2B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Trmt2b (tRNA methyltransferase 2 homolog B)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TRMT2B (tRNA methyltransferase 2 homolog B)
Canis lupus familiaris (dog) : TRMT2B (tRNA methyltransferase 2 homolog B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trmt2b (tRNA methyltransferase 2 homolog B)
Sus scrofa (pig) : TRMT2B (tRNA methyltransferase 2 homolog B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,973,359 - 101,052,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,264,334 - 100,307,105 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,151,187 - 100,193,726 (-)NCBINCBI36hg18NCBI36
Build 34X100,070,692 - 100,113,215NCBI
CeleraX100,783,109 - 100,825,878 (-)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX90,068,401 - 90,112,076 (-)NCBIHuRef
CHM1_1X100,157,442 - 100,200,214 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TRMT2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350620
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.