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Gene: H2AC21 (H2A clustered histone 21) Homo sapiens
Symbol: H2AC21
Name: H2A clustered histone 21
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2AB; HIST2H2AB; histone 2, H2ab; histone cluster 2 H2A family member b; histone cluster 2, H2ab; histone H2A type 2-B
Mus musculus (house mouse) : Hist2h2ab (histone cluster 2, H2ab)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist2h2ab (histone cluster 2 H2A family member b)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102024203 (histone H2A type 2-B)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985779 (histone H2A type 2-B)
Sus scrofa (pig) : LOC100154181 (histone H2A type 2-B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381149,887,469 - 149,887,916 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371149,859,019 - 149,859,466 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,125,643 - 148,126,090 (-)NCBINCBI36hg18NCBI36
Build 341146,672,091 - 146,672,539NCBI
Celera1122,975,244 - 122,975,691 (-)NCBI
Cytogenetic Map1q21.2NCBI
HuRef1121,239,995 - 121,240,442 (-)NCBIHuRef
CHM1_11151,255,595 - 151,256,042 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2AC21
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350646
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.