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Gene: ISCA1 (iron-sulfur cluster assembly 1) Homo sapiens
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Symbol: ISCA1
Name: iron-sulfur cluster assembly 1
Description: Predicted to have 2 iron, 2 sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to localize to the mitochondrion. Implicated in multiple mitochondrial dysfunctions syndrome 5.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HBLD2; HESB like domain containing 2; HESB-like domain-containing protein 2; hIscA; iron sulfur assembly protein IscA; iron-sulfur assembly protein IscA; iron-sulfur cluster assembly 1 homolog, mitochondrial; ISA1; MGC4276; MMDS5; RP11-507D14.2
Orthologs:
Mus musculus (house mouse) : Isca1 (iron-sulfur cluster assembly 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Isca1 (iron-sulfur cluster assembly 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isca1 (iron-sulfur cluster assembly 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ISCA1 (iron-sulfur cluster assembly 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Isca1 (iron-sulfur cluster assembly 1)
Sus scrofa (pig) : ISCA1 (iron-sulfur cluster assembly 1)
more info ...
Related Pseudogenes: ISCA1P1   ISCA1P2   ISCA1P3   ISCA1P4   ISCA1P5   ISCA1P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38986,264,546 - 86,282,538 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37988,879,461 - 88,897,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36988,069,281 - 88,087,310 (-)NCBINCBI36hg18NCBI36
Build 34986,109,015 - 86,127,044NCBI
Celera959,449,572 - 59,467,604 (-)NCBI
Cytogenetic Map9q21.33NCBI
HuRef958,702,212 - 58,720,322 (-)NCBIHuRef
CHM1_1989,025,905 - 89,043,932 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ISCA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350652
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.