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Gene: EPHA8 (EPH receptor A8) Homo sapiens
Symbol: EPHA8
Name: EPH receptor A8
Description: Predicted to have GPI-linked ephrin receptor activity and transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; neuron development; and positive regulation of phosphorylation. Predicted to localize to integral component of plasma membrane; neuron projection; and receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EEK; EK3; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; EPH-like kinase 3; ephrin type-A receptor 8; HEK3; hydroxyaryl-protein kinase; KIAA1459; protein-tyrosine kinase; tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
Mus musculus (house mouse) : Epha8 (Eph receptor A8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Epha8 (Eph receptor A8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epha8 (EPH receptor A8)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHA8 (EPH receptor A8)
Canis lupus familiaris (dog) : EPHA8 (EPH receptor A8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epha8 (EPH receptor A8)
Sus scrofa (pig) : EPHA8 (EPH receptor A8)
Chlorocebus sabaeus (African green monkey) : EPHA8 (EPH receptor A8)
Heterocephalus glaber (naked mole-rat) : Epha8 (EPH receptor A8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl122,563,489 - 22,603,595 (+)EnsemblGRCh38hg38GRCh38
GRCh38122,563,489 - 22,603,595 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,890,004 - 22,930,087 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,762,591 - 22,802,674 (+)NCBINCBI36hg18NCBI36
Build 34122,635,309 - 22,675,393NCBI
Celera121,213,404 - 21,254,789 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef121,133,248 - 21,174,608 (+)NCBIHuRef
CHM1_1123,008,057 - 23,042,609 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on EPHA8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350663
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.