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Gene: SLC22A18 (solute carrier family 22 member 18) Homo sapiens
Symbol: SLC22A18
Name: solute carrier family 22 member 18
Description: Exhibits transmembrane transporter activity and ubiquitin protein ligase binding activity. Involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Localizes to apical plasma membrane; cytoplasm; and nuclear envelope. Implicated in breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Beckwith-Wiedemann syndrome chromosome region 1, candidate A; BWR1A; BWSCR1A; DKFZp667A184; efflux transporter-like protein; HET; imprinted multi-membrane spanning polyspecific transporter-related protein 1; imprinted multi-membrane-spanning polyspecific transporter-related protein 1; IMPT1; ITM; ORCTL-2; ORCTL2; organic cation transporter-like 2; organic cation transporter-like protein 2; p45 Beckwith-Wiedemann region 1A; p45-Beckwith-Wiedemann region 1 A; p45-BWR1A; SLC22A1L; solute carrier family 22 (organic cation transporter), member 1-like; solute carrier family 22 member 1-like; solute carrier family 22, member 18; TSSC5; tumor-suppressing STF cDNA 5 protein; tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein
Mus musculus (house mouse) : Slc22a18 (solute carrier family 22 (organic cation transporter), member 18)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc22a18 (solute carrier family 22, member 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a18 (solute carrier family 22 member 18)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A18 (solute carrier family 22 member 18)
Canis lupus familiaris (dog) : SLC22A18 (solute carrier family 22 member 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a18 (solute carrier family 22 member 18)
Sus scrofa (pig) : SLC22A18 (solute carrier family 22 member 18)
Chlorocebus sabaeus (African green monkey) : SLC22A18 (solute carrier family 22 member 18)
Heterocephalus glaber (naked mole-rat) : Slc22a18 (solute carrier family 22 member 18)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl112,899,721 - 2,925,246 (+)EnsemblGRCh38hg38GRCh38
GRCh38112,899,691 - 2,925,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,920,951 - 2,946,476 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,877,527 - 2,903,052 (+)NCBINCBI36hg18NCBI36
Build 34112,877,526 - 2,903,051NCBI
Celera112,955,665 - 2,981,127 (+)NCBI
Cytogenetic Map11p15.4NCBI
HuRef112,709,509 - 2,734,907 (+)NCBIHuRef
CHM1_1112,919,878 - 2,945,340 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC22A18
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350768
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.