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Gene: GRK6 (G protein-coupled receptor kinase 6) Homo sapiens
Symbol: GRK6
Name: G protein-coupled receptor kinase 6
Description: Exhibits beta-adrenergic receptor kinase activity. Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of G protein-coupled receptor signaling pathway. Localizes to the membrane. Implicated in Parkinson's disease. Biomarker of rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ32135; g protein-coupled receptor kinase GRK6; GPRK6
Mus musculus (house mouse) : Grk6 (G protein-coupled receptor kinase 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grk6 (G protein-coupled receptor kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grk6 (G protein-coupled receptor kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : GRK6 (G protein-coupled receptor kinase 6)
Canis lupus familiaris (dog) : GRK6 (G protein-coupled receptor kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grk6 (G protein-coupled receptor kinase 6)
Sus scrofa (pig) : GRK6 (G protein-coupled receptor kinase 6)
more info ...
Related Pseudogenes: GRK6P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh385177,426,496 - 177,442,891 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375176,853,687 - 176,869,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,786,293 - 176,802,456 (+)NCBINCBI36hg18NCBI36
Build 345176,786,293 - 176,802,437NCBI
Celera5171,631,577 - 171,647,739 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5171,774,137 - 171,790,304 (+)NCBIHuRef
CHM1_15176,287,084 - 176,303,247 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GRK6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350771
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.