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Gene: ATF5 (activating transcription factor 5) Homo sapiens
Symbol: ATF5
Name: activating transcription factor 5
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and tubulin binding activity. Involved in several processes, including fat cell differentiation; regulation of cell cycle process; and regulation of transcription, DNA-templated. Localizes to centrosome; cytosol; and nucleoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFX; cAMP-dependent transcription factor ATF-5; cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; transcription factor ATFx
Mus musculus (house mouse) : Atf5 (activating transcription factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atf5 (activating transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf5 (activating transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF5 (activating transcription factor 5)
Canis lupus familiaris (dog) : ATF5 (activating transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf5 (activating transcription factor 5)
Sus scrofa (pig) : ATF5 (activating transcription factor 5)
Chlorocebus sabaeus (African green monkey) : ATF5 (activating transcription factor 5)
Heterocephalus glaber (naked mole-rat) : Atf5 (activating transcription factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1949,928,702 - 49,933,935 (+)EnsemblGRCh38hg38GRCh38
GRCh381949,928,702 - 49,933,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371950,431,959 - 50,437,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,124,272 - 55,129,003 (+)NCBINCBI36hg18NCBI36
Build 341955,124,271 - 55,129,003NCBI
Celera1947,301,474 - 47,306,707 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,808,214 - 46,813,450 (+)NCBIHuRef
CHM1_11950,433,787 - 50,439,041 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ATF5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350993
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.