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Gene: SFRP4 (secreted frizzled related protein 4) Homo sapiens
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Symbol: SFRP4
Name: secreted frizzled related protein 4
Description: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: frizzled protein, human endometrium; FRP-4; FRPHE; FRZB-2; MGC26498; PYL; secreted frizzled-related protein 4; sFRP-4
Orthologs:
Mus musculus (house mouse) : Sfrp4 (secreted frizzled-related protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sfrp4 (secreted frizzled-related protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfrp4 (secreted frizzled related protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SFRP4 (secreted frizzled related protein 4)
Canis lupus familiaris (dog) : SFRP4 (secreted frizzled related protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfrp4 (secreted frizzled related protein 4)
Sus scrofa (pig) : SFRP4 (secreted frizzled related protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38737,905,932 - 37,916,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37737,945,534 - 37,956,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36737,912,068 - 37,922,902 (-)NCBINCBI36hg18NCBI36
Build 34737,718,782 - 37,729,617NCBI
Celera737,930,244 - 37,941,234 (-)NCBI
Cytogenetic Map7p14.1NCBI
HuRef737,825,879 - 37,836,854 (-)NCBIHuRef
CHM1_1737,945,489 - 37,956,481 (-)NCBICHM1_1
CRA_TCAGchr7v2737,983,430 - 37,994,420 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SFRP4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350997
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.