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Gene: ZBP1 (Z-DNA binding protein 1) Homo sapiens
Symbol: ZBP1
Name: Z-DNA binding protein 1
CRRD ID: 1351033
Description: Exhibits DNA binding activity and identical protein binding activity. Involved in defense response to virus and positive regulation of necroptotic process. Localizes to cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C20orf183; DAI; DLM-1; DLM1; DNA-dependent activator of IFN-regulatory factors; DNA-dependent activator of interferon regulatory factors; DNA-dependent activator of IRFs; tumor stroma and activated macrophage protein DLM-1; Z-DNA-binding protein 1
Mus musculus (house mouse) : Zbp1 (Z-DNA binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zbp1 (Z-DNA binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zbp1 (Z-DNA binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZBP1 (Z-DNA binding protein 1)
Canis lupus familiaris (dog) : ZBP1 (Z-DNA binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zbp1 (Z-DNA binding protein 1)
Sus scrofa (pig) : ZBP1 (Z-DNA binding protein 1)
Chlorocebus sabaeus (African green monkey) : ZBP1 (Z-DNA binding protein 1)
Heterocephalus glaber (naked mole-rat) : Zbp1 (Z-DNA binding protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2057,603,846 - 57,620,576 (-)EnsemblGRCh38hg38GRCh38
GRCh382057,603,852 - 57,620,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372056,178,902 - 56,195,632 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362055,612,308 - 55,628,935 (-)NCBINCBI36hg18NCBI36
Build 342055,612,309 - 55,628,935NCBI
Celera2052,919,278 - 52,936,016 (-)NCBI
Cytogenetic Map20q13.31NCBI
HuRef2052,960,880 - 52,977,617 (-)NCBIHuRef
CHM1_12056,079,953 - 56,096,848 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ZBP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351033
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.