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Gene: SENP2 (SUMO specific peptidase 2) Homo sapiens
Symbol: SENP2
Name: SUMO specific peptidase 2
Description: Exhibits SUMO-specific endopeptidase activity. Involved in protein destabilization; protein desumoylation; and regulation of protein ubiquitination. Localizes to the cytosol and nuclear pore. Predicted to colocalize with the PML body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AXAM2; DKFZp762A2316; KIAA1331; sentrin (SUMO1) specific peptidase 2; sentrin-specific protease 2; sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; SMT3IP2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2
Mus musculus (house mouse) : Senp2 (SUMO/sentrin specific peptidase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Senp2 (SUMO specific peptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Senp2 (SUMO specific peptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SENP2 (SUMO specific peptidase 2)
Canis lupus familiaris (dog) : SENP2 (SUMO specific peptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Senp2 (SUMO specific peptidase 2)
Sus scrofa (pig) : SENP2 (SUMO specific peptidase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh383185,586,295 - 185,633,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373185,300,284 - 185,348,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,786,725 - 186,831,583 (+)NCBINCBI36hg18NCBI36
Build 343186,786,732 - 186,831,585NCBI
Celera3183,741,683 - 183,786,630 (+)NCBI
Cytogenetic Map3q27.2NCBI
HuRef3182,713,166 - 182,758,813 (+)NCBIHuRef
CHM1_13185,267,116 - 185,311,866 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SENP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351152
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.