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Gene: SENP2 (SUMO specific peptidase 2) Homo sapiens
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Symbol: SENP2
Name: SUMO specific peptidase 2
Description: Exhibits SUMO-specific endopeptidase activity. Involved in protein destabilization; protein desumoylation; and regulation of protein ubiquitination. Localizes to the cytosol and nuclear pore. Predicted to colocalize with the PML body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AXAM2; DKFZp762A2316; KIAA1331; sentrin (SUMO1) specific peptidase 2; sentrin-specific protease 2; sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; SMT3IP2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2
Orthologs:
Mus musculus (house mouse) : Senp2 (SUMO/sentrin specific peptidase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Senp2 (SUMO specific peptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Senp2 (SUMO specific peptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SENP2 (SUMO specific peptidase 2)
Canis lupus familiaris (dog) : SENP2 (SUMO specific peptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Senp2 (SUMO specific peptidase 2)
Sus scrofa (pig) : SENP2 (SUMO specific peptidase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,586,295 - 185,633,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373185,300,284 - 185,348,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,786,725 - 186,831,583 (+)NCBINCBI36hg18NCBI36
Build 343186,786,732 - 186,831,585NCBI
Celera3183,741,683 - 183,786,630 (+)NCBI
Cytogenetic Map3q27.2NCBI
HuRef3182,713,166 - 182,758,813 (+)NCBIHuRef
CHM1_13185,267,116 - 185,311,866 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SENP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351152
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.