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Gene: ENO4 (enolase 4) Homo sapiens
Symbol: ENO4
Name: enolase 4
Description: Predicted to have phosphopyruvate hydratase activity. Predicted to be involved in several processes, including flagellated sperm motility; glycolytic process; and regulation of vacuole fusion, non-autophagic. Predicted to localize to phosphopyruvate hydratase complex and sperm principal piece; INTERACTS WITH cisplatin; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2-phospho-D-glycerate hydro-lyase; AC023283.3; C10orf134; DKFZP781N1041; enolase family member 4; enolase-like protein ENO4
Mus musculus (house mouse) : Eno4 (enolase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eno4 (enolase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eno4 (enolase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ENO4 (enolase 4)
Canis lupus familiaris (dog) : ENO4 (enolase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eno4 (enolase 4)
Sus scrofa (pig) : ENO4 (enolase 4)
Chlorocebus sabaeus (African green monkey) : ENO4 (enolase 4)
Heterocephalus glaber (naked mole-rat) : Eno4 (enolase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10116,849,499 - 116,911,788 (+)EnsemblGRCh38hg38GRCh38
GRCh3810116,848,230 - 116,911,803 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710118,608,741 - 118,642,112 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,598,662 - 118,632,102 (+)NCBINCBI36hg18NCBI36
Celera10112,338,464 - 112,371,477 (+)NCBI
Cytogenetic Map10q25.3NCBI
HuRef10112,237,174 - 112,270,284 (+)NCBIHuRef
CHM1_110118,892,138 - 118,925,231 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ENO4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351322
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.