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Gene: MAGEB1 (MAGE family member B1) Homo sapiens
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Symbol: MAGEB1
Name: MAGE family member B1
Description: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 3.1; cancer/testis antigen family 3, member 1; CT3.1; DAM10; DSS-AHC critical interval MAGE superfamily 10; DSS/AHC critical interval MAGE superfamily 10; MAGE-B1 antigen; MAGE-Xp; MAGE-XP antigen; MAGEL1; melanoma antigen family B, 1; melanoma antigen family B1; melanoma-associated antigen B1; MGC9322
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,243,731 - 30,252,038 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,261,848 - 30,270,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,171,769 - 30,180,076 (+)NCBINCBI36hg18NCBI36
Build 34X30,021,504 - 30,029,812NCBI
CeleraX34,383,468 - 34,391,775 (+)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX27,998,737 - 28,007,043 (+)NCBIHuRef
CHM1_1X30,292,728 - 30,301,035 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351406
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.