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Gene: AMD1 (adenosylmethionine decarboxylase 1) Homo sapiens
Symbol: AMD1
Name: adenosylmethionine decarboxylase 1
Description: Predicted to have adenosylmethionine decarboxylase activity and putrescine binding activity. Predicted to be involved in spermidine biosynthetic process and spermine biosynthetic process. Predicted to localize to the cytosol. Implicated in lung non-small cell carcinoma. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADOMETDC; AMD; DKFZp313L1234; FLJ26964; S-adenosylmethionine decarboxylase 1; S-adenosylmethionine decarboxylase proenzyme; SAMDC
Mus musculus (house mouse) : Amd1 (S-adenosylmethionine decarboxylase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Amd1 (adenosylmethionine decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amd1 (adenosylmethionine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMD1 (adenosylmethionine decarboxylase 1)
Canis lupus familiaris (dog) : AMD1 (adenosylmethionine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amd1 (adenosylmethionine decarboxylase 1)
Sus scrofa (pig) : AMD1 (adenosylmethionine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : AMD1 (adenosylmethionine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Amd1 (adenosylmethionine decarboxylase 1)
more info ...
Related Pseudogenes: AMD1P1   AMD1P2   AMD1P3   AMD1P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6110,874,770 - 110,898,879 (+)EnsemblGRCh38hg38GRCh38
GRCh386110,814,621 - 110,895,713 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,135,823 - 111,216,916 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366111,302,680 - 111,323,606 (+)NCBINCBI36hg18NCBI36
Build 346111,302,680 - 111,323,599NCBI
Celera6111,942,595 - 111,963,525 (+)NCBI
Cytogenetic Map6q21NCBI
HuRef6108,767,311 - 108,788,282 (+)NCBIHuRef
CHM1_16111,398,990 - 111,480,044 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on AMD1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351440
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.