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Gene: FGF23 (fibroblast growth factor 23) Homo sapiens
Symbol: FGF23
Name: fibroblast growth factor 23
Description: Predicted to have growth factor activity and type 1 fibroblast growth factor receptor binding activity. Involved in several processes, including negative regulation of ossification; positive regulation of vitamin D 24-hydroxylase activity; and vitamin D catabolic process. Localizes to the extracellular space. Implicated in autosomal dominant hypophosphatemic rickets. Biomarker of inflammatory bowel disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADHR; FGF-23; FGFN; HFTC2; HPDR2; HYPF; phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; tumor-derived hypophosphatemia-inducing factor
Mus musculus (house mouse) : Fgf23 (fibroblast growth factor 23)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgf23 (fibroblast growth factor 23)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf23 (fibroblast growth factor 23)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF23 (fibroblast growth factor 23)
Canis lupus familiaris (dog) : FGF23 (fibroblast growth factor 23)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf23 (fibroblast growth factor 23)
Sus scrofa (pig) : FGF23 (fibroblast growth factor 23)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38124,368,227 - 4,379,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,477,393 - 4,488,894 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,347,654 - 4,359,155 (-)NCBINCBI36hg18NCBI36
Build 34124,347,653 - 4,359,155NCBI
Celera126,099,463 - 6,110,952 (-)NCBI
Cytogenetic Map12p13.32NCBI
HuRef124,334,034 - 4,345,523 (-)NCBIHuRef
CHM1_1124,477,002 - 4,488,504 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FGF23
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351456
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.