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Gene: FGF23 (fibroblast growth factor 23) Homo sapiens
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Symbol: FGF23
Name: fibroblast growth factor 23
Description: Predicted to have growth factor activity and type 1 fibroblast growth factor receptor binding activity. Involved in several processes, including negative regulation of ossification; positive regulation of vitamin D 24-hydroxylase activity; and vitamin D catabolic process. Localizes to the extracellular space. Implicated in autosomal dominant hypophosphatemic rickets. Biomarker of inflammatory bowel disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADHR; FGF-23; FGFN; HFTC2; HPDR2; HYPF; phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; tumor-derived hypophosphatemia-inducing factor
Orthologs:
Mus musculus (house mouse) : Fgf23 (fibroblast growth factor 23)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgf23 (fibroblast growth factor 23)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf23 (fibroblast growth factor 23)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF23 (fibroblast growth factor 23)
Canis lupus familiaris (dog) : FGF23 (fibroblast growth factor 23)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf23 (fibroblast growth factor 23)
Sus scrofa (pig) : FGF23 (fibroblast growth factor 23)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,368,227 - 4,379,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,477,393 - 4,488,894 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,347,654 - 4,359,155 (-)NCBINCBI36hg18NCBI36
Build 34124,347,653 - 4,359,155NCBI
Celera126,099,463 - 6,110,952 (-)NCBI
Cytogenetic Map12p13.32NCBI
HuRef124,334,034 - 4,345,523 (-)NCBIHuRef
CHM1_1124,477,002 - 4,488,504 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FGF23
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351456
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.