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Gene: ITGA5 (integrin subunit alpha 5) Homo sapiens
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Symbol: ITGA5
Name: integrin subunit alpha 5
CRRD ID: 1351478
Description: Predicted to have platelet-derived growth factor receptor binding activity and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including cell surface receptor signaling pathway; negative regulation of anoikis; and wound healing, spreading of epidermal cells. Localizes to cell surface; focal adhesion; and integrin alpha5-beta1 complex. Colocalizes with cell-cell junction and ruffle membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD49 antigen-like family member E; CD49e; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; integrin alpha 5; integrin alpha-5; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; very late activation protein 5, alpha subunit; VLA-5; VLA5A
Orthologs:
Mus musculus (house mouse) : Itga5 (integrin alpha 5 (fibronectin receptor alpha))  MGI  Alliance
Rattus norvegicus (Norway rat) : Itga5 (integrin subunit alpha 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga5 (integrin subunit alpha 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA5 (integrin subunit alpha 5)
Canis lupus familiaris (dog) : ITGA5 (integrin subunit alpha 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga5 (integrin subunit alpha 5)
Sus scrofa (pig) : ITGA5 (integrin subunit alpha 5)
Chlorocebus sabaeus (African green monkey) : ITGA5 (integrin subunit alpha 5)
Heterocephalus glaber (naked mole-rat) : Itga5 (integrin subunit alpha 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1254,395,261 - 54,419,266 (-)EnsemblGRCh38hg38GRCh38
GRCh381254,395,261 - 54,419,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371254,789,045 - 54,813,050 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,075,312 - 53,099,317 (-)NCBINCBI36hg18NCBI36
Build 341253,075,313 - 53,099,317NCBI
Celera1254,440,888 - 54,464,894 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1251,828,142 - 51,852,148 (-)NCBIHuRef
CHM1_11254,755,737 - 54,779,741 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
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Additional Information

External Database Links
Nomenclature History
 
More on ITGA5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351478
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.