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Gene: XK (X-linked Kx blood group) Homo sapiens
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Symbol: XK
Name: X-linked Kx blood group
Description: This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Kell blood group precursor (McLeod phenotype); kell complex 37 kDa component; KX; Kx antigen; Kx blood group antigen; MCLDS; membrane transport protein XK; NA; NAC; neuroacanthocytosis; neurocanthocytosis; truncated X-linked Kx blood group; X1k; XK, Kell blood group complex subunit (McLeod syndrome); XK-related protein 1; XKR1
Orthologs:
Mus musculus (house mouse) : Xk (X-linked Kx blood group)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xk (X-linked Kx blood group)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xk (X-linked Kx blood group)
Pan paniscus (bonobo/pygmy chimpanzee) : XK (X-linked Kx blood group)
Canis lupus familiaris (dog) : XK (X-linked Kx blood group)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xk (X-linked Kx blood group)
Sus scrofa (pig) : XK (X-linked Kx blood group)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X37,685,686 - 37,732,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X37,545,133 - 37,591,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X37,430,052 - 37,476,322 (+)NCBINCBI36hg18NCBI36
Build 34X37,301,324 - 37,347,594NCBI
CeleraX41,682,795 - 41,729,061 (+)NCBI
Cytogenetic MapXp21.1NCBI
HuRefX35,290,888 - 35,336,107 (+)NCBIHuRef
CHM1_1X37,576,264 - 37,622,522 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351512
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.