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Gene: FBXO31 (F-box protein 31) Homo sapiens
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Symbol: FBXO31
Name: F-box protein 31
Description: Exhibits cyclin binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; anaphase-promoting complex-dependent catabolic process; and mitotic G1 DNA damage checkpoint. Localizes to the SCF ubiquitin ligase complex. Implicated in autosomal recessive non-syndromic intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434B027; DKFZp434J1815; F-box only protein 31; FBX14; Fbx31; FBXO14; FLJ22477; MGC15419; MGC9527; MRT45; pp2386; putative breast cancer tumor-suppressor; SCF ubiquitin ligase specificity factor
Orthologs:
Mus musculus (house mouse) : Fbxo31 (F-box protein 31)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo31 (F-box protein 31)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo31 (F-box protein 31)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO31 (F-box protein 31)
Canis lupus familiaris (dog) : FBXO31 (F-box protein 31)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo31 (F-box protein 31)
Sus scrofa (pig) : FBXO31 (F-box protein 31)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381687,326,987 - 87,392,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371687,362,942 - 87,425,708 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,920,443 - 85,974,864 (-)NCBINCBI36hg18NCBI36
Build 341685,920,444 - 85,974,864NCBI
Celera1671,659,646 - 71,722,476 (-)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1673,106,044 - 73,168,796 (-)NCBIHuRef
CHM1_11688,772,405 - 88,837,523 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FBXO31
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351564
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.