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Gene: LCMT1 (leucine carboxyl methyltransferase 1) Homo sapiens
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Symbol: LCMT1
Name: leucine carboxyl methyltransferase 1
Description: Exhibits protein C-terminal carboxyl O-methyltransferase activity. Involved in several processes, including C-terminal protein methylation; negative regulation of protein complex assembly; and regulation of mitotic cell cycle spindle assembly checkpoint. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [phosphatase 2A protein]-leucine-carboxy methyltransferase; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1; CGI-68; LCMT; PPMT1; protein phosphatase methyltransferase 1; protein-leucine O-methyltransferase
Orthologs:
Mus musculus (house mouse) : Lcmt1 (leucine carboxyl methyltransferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lcmt1 (leucine carboxyl methyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lcmt1 (leucine carboxyl methyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LCMT1 (leucine carboxyl methyltransferase 1)
Canis lupus familiaris (dog) : LCMT1 (leucine carboxyl methyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lcmt1 (leucine carboxyl methyltransferase 1)
Sus scrofa (pig) : LCMT1 (leucine carboxyl methyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381625,111,702 - 25,178,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371625,123,047 - 25,189,551 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361625,030,548 - 25,097,052 (+)NCBINCBI36hg18NCBI36
Build 341625,030,675 - 25,097,050NCBI
Celera1623,903,957 - 23,969,431 (+)NCBI
Cytogenetic Map16p12.1NCBI
HuRef1623,216,333 - 23,282,516 (+)NCBIHuRef
CHM1_11626,136,800 - 26,203,307 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LCMT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351587
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.