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Gene: FCN1 (ficolin 1) Homo sapiens
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Symbol: FCN1
Name: ficolin 1
Description: Exhibits G protein-coupled receptor binding activity; sialic acid binding activity; and signaling pattern recognition receptor activity. Involved in several processes, including cell surface pattern recognition receptor signaling pathway; positive regulation of interleukin-8 secretion; and protein localization to cell surface. Localizes to the extrinsic component of external side of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: collagen/fibrinogen domain-containing protein 1; FCNM; ficolin (collagen/fibrinogen domain containing) 1; ficolin (collagen/fibrinogen domain-containing) 1; ficolin-1; ficolin-A; ficolin-alpha; M-ficolin
Orthologs:
Mus musculus (house mouse) : Fcnb (ficolin B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fcnb (ficolin B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fcn1 (ficolin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FCN1 (ficolin 1)
Canis lupus familiaris (dog) : FCN2 (ficolin 2)
Sus scrofa (pig) : FCN2 (ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,903,232 - 134,917,912 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379137,797,711 - 137,809,849 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369136,941,253 - 136,949,630 (-)NCBINCBI36hg18NCBI36
Build 349135,027,380 - 135,035,754NCBI
Celera9108,315,253 - 108,323,628 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9107,265,062 - 107,273,437 (-)NCBIHuRef
CHM1_19137,950,267 - 137,958,642 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FCN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351597
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.