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Gene: NAMPT (nicotinamide phosphoribosyltransferase) Homo sapiens
Symbol: NAMPT
Name: nicotinamide phosphoribosyltransferase
CRRD ID: 1351636
Description: Exhibits identical protein binding activity. Involved in positive regulation of nitric-oxide synthase biosynthetic process and positive regulation of transcription by RNA polymerase II. Localizes to cell junction and nuclear speck. Implicated in transient cerebral ischemia. Biomarker of carotid artery disease; coronary artery disease; obesity; pulmonary hypertension; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1110035O14Rik; DKFZp666B131; MGC117256; NAmPRTase; PBEF; PBEF1; pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1; VF; VISFATIN
Mus musculus (house mouse) : Nampt (nicotinamide phosphoribosyltransferase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nampt (nicotinamide phosphoribosyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nampt (nicotinamide phosphoribosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : NAMPT (nicotinamide phosphoribosyltransferase)
Canis lupus familiaris (dog) : NAMPT (nicotinamide phosphoribosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nampt (nicotinamide phosphoribosyltransferase)
Sus scrofa (pig) : NAMPT (nicotinamide phosphoribosyltransferase)
Chlorocebus sabaeus (African green monkey) : NAMPT (nicotinamide phosphoribosyltransferase)
Heterocephalus glaber (naked mole-rat) : Nampt (nicotinamide phosphoribosyltransferase)
more info ...
Related Pseudogenes: NAMPTP1   NAMPTP2   NAMPTP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl7106,248,298 - 106,286,326 (-)EnsemblGRCh38hg38GRCh38
GRCh387106,248,298 - 106,284,983 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377105,888,731 - 105,926,373 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367105,675,967 - 105,712,874 (-)NCBINCBI36hg18NCBI36
Build 347105,495,899 - 105,519,318NCBI
Celera7100,694,260 - 100,731,169 (-)NCBI
Cytogenetic Map7q22.3NCBI
HuRef7100,248,062 - 100,285,253 (-)NCBIHuRef
CHM1_17105,822,212 - 105,859,137 (-)NCBICHM1_1
CRA_TCAGchr7v27105,249,752 - 105,286,646 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NAMPT
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351636
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.