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Gene: IL23R (interleukin 23 receptor) Homo sapiens
Symbol: IL23R
Name: interleukin 23 receptor
Description: Contributes to interleukin-12 receptor binding activity; interleukin-23 binding activity; and interleukin-23 receptor activity. Involved in several processes, including positive regulation of defense response to virus by host; regulation of cytokine production; and response to interferon-gamma. Localizes to interleukin-23 receptor complex. Implicated in several diseases, including Behcet's disease; autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); inflammatory bowel disease (multiple); and psoriasis (multiple). Biomarker of Sjogren's syndrome and systemic lupus erythematosus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IL-23 receptor; interleukin-23 receptor
Mus musculus (house mouse) : Il23r (interleukin 23 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il23r (interleukin 23 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il23r (interleukin 23 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL23R (interleukin 23 receptor)
Canis lupus familiaris (dog) : IL23R (interleukin 23 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il23r (interleukin 23 receptor)
Sus scrofa (pig) : IL23R (interleukin 23 receptor)
Chlorocebus sabaeus (African green monkey) : IL23R (interleukin 23 receptor)
Heterocephalus glaber (naked mole-rat) : Il23r (interleukin 23 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl167,138,907 - 67,259,979 (+)EnsemblGRCh38hg38GRCh38
GRCh38167,138,639 - 67,259,979 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37167,604,590 - 67,725,662 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,404,757 - 67,498,250 (+)NCBINCBI36hg18NCBI36
Build 34167,344,189 - 67,437,669NCBI
Celera165,922,104 - 66,015,428 (+)NCBI
Cytogenetic Map1p31.3NCBI
HuRef165,740,552 - 65,835,548 (+)NCBIHuRef
CHM1_1167,747,479 - 67,841,006 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL23R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351657
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.