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Gene: TYRP1 (tyrosinase related protein 1) Homo sapiens
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Symbol: TYRP1
Name: tyrosinase related protein 1
Description: Exhibits monophenol monooxygenase activity. Involved in positive regulation of melanin biosynthetic process. Localizes to the clathrin-coated endocytic vesicle membrane and endosome membrane. Implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5,6-dihydroxyindole-2-carboxylic acid oxidase; b-PROTEIN; CAS2; catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; melanoma antigen gp75; OCA3; SHEP11; TRP; TRP-1; TRP1; tyrosinase-related protein 1; TYRP
Orthologs:
Mus musculus (house mouse) : Tyrp1 (tyrosinase-related protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tyrp1 (tyrosinase-related protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyrp1 (tyrosinase related protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TYRP1 (tyrosinase related protein 1)
Canis lupus familiaris (dog) : TYRP1 (tyrosinase related protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyrp1 (tyrosinase related protein 1)
Sus scrofa (pig) : TYRP1 (tyrosinase related protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38912,693,375 - 12,710,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37912,693,385 - 12,710,285 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36912,683,449 - 12,700,258 (+)NCBINCBI36hg18NCBI36
Build 34912,683,448 - 12,700,258NCBI
Celera912,625,996 - 12,642,868 (+)NCBI
Cytogenetic Map9p23NCBI
HuRef912,658,087 - 12,674,962 (+)NCBIHuRef
CHM1_1912,693,770 - 12,710,634 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TYRP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351708
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.