Symbol:
RAB15
Name:
RAB15, member RAS oncogene family
Description:
Predicted to have GTPase activity. Involved in positive regulation of regulated secretory pathway. Localizes to the cilium; endosome membrane; and perinuclear region of cytoplasm; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
RAB15, member RAS onocogene family; ras-related protein Rab-15; Ras-related protein Rab-15 isoform AN1; Ras-related protein Rab-15 isoform AN2; Ras-related protein Rab-15 isoform AN3
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Rab15 (RAB15, member RAS oncogene family) HGNC
EggNOG, Ensembl, HGNC, Inparanoid, NCBI, OMA, Panther, Treefam
Rattus norvegicus (Norway rat):
Rab15 (RAB15, member RAS oncogene family) HGNC
EggNOG, Ensembl, Inparanoid, NCBI, OMA, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):
Rab15 (RAB15, member RAS oncogene family) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
RAB15 (RAB15, member RAS oncogene family) NCBI
Ortholog
Canis lupus familiaris (dog):
RAB15 (RAB15, member RAS oncogene family) HGNC
EggNOG, Ensembl, Inparanoid, NCBI, OMA, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rab15 (RAB15, member RAS oncogene family) NCBI
Ortholog
Sus scrofa (pig):
RAB15 (RAB15, member RAS oncogene family) HGNC
EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Other homologs 2
Rattus norvegicus (Norway rat):
Rab26 (RAB26, member RAS oncogene family) HGNC
Panther
Mus musculus (house mouse):
Rab26 (RAB26, member RAS oncogene family) HGNC
Panther
Rattus norvegicus (Norway rat):
Rab33b (RAB33B, member RAS oncogene family) HGNC
Panther
Mus musculus (house mouse):
Rab37 (RAB37, member RAS oncogene family) HGNC
Panther
Mus musculus (house mouse):
Rab33b (RAB33B, member RAS oncogene family) HGNC
Panther
Mus musculus (house mouse):
Rab33a (RAB33A, member RAS oncogene family) HGNC
Panther
Rattus norvegicus (Norway rat):
Rab33a (RAB33A, member RAS oncogene family) HGNC
Panther
Rattus norvegicus (Norway rat):
Rab37 (RAB37, member RAS oncogene family) HGNC
Panther
Canis lupus familiaris (dog):
RAB26 (RAB26, member RAS oncogene family) HGNC
Panther
Canis lupus familiaris (dog):
RAB33B (RAB33B, member RAS oncogene family) HGNC
Panther
Canis lupus familiaris (dog):
RAB37 (RAB37, member RAS oncogene family) HGNC
Panther
Canis lupus familiaris (dog):
RAB33A (RAB33A, member RAS oncogene family) HGNC
Panther
Sus scrofa (pig):
RAB33B (RAB33B, member RAS oncogene family) HGNC
Panther
Sus scrofa (pig):
RAB37 (RAB37, member RAS oncogene family) HGNC
Panther
Sus scrofa (pig):
RAB33A (RAB33A, member RAS oncogene family) HGNC
Panther
Sus scrofa (pig):
RAB26 (RAB26, member RAS oncogene family) HGNC
Panther
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rab15 (RAB15, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Rab15 (RAB15, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
rab15 (RAB15, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Saccharomyces cerevisiae (baker's yeast):
SEC4
Alliance
DIOPT (Ensembl Compara, PANTHER, PhylomeDB, TreeFam)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 64,945,816 - 64,972,336 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 14 65,412,532 - 65,439,016 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 64,482,287 - 64,508,551 (-) NCBI NCBI36 hg18 NCBI36 Build 34 14 64,482,287 - 64,508,551 NCBI Celera 14 45,467,116 - 45,493,459 (-) NCBI Cytogenetic Map 14 q23.3 NCBI HuRef 14 45,582,156 - 45,608,228 (-) NCBI HuRef CHM1_1 14 65,350,701 - 65,377,061 (-) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
(-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of RAB15 protein CTD PMID:31195006 17beta-estradiol multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of RAB15 mRNA CTD PMID:17404688 17beta-estradiol increases expression ISO RGD:1332034 6480464 Estradiol results in increased expression of RAB15 mRNA CTD PMID:19484750 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1332034 6480464 Tetrachlorodibenzodioxin affects the expression of RAB15 mRNA CTD PMID:21570461 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:735172 6480464 Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA CTD PMID:23537331 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1332034 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of RAB15 mRNA CTD PMID:20188158 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid decreases expression EXP 6480464 Am 580 results in decreased expression of RAB15 mRNA CTD PMID:16982809 6-propyl-2-thiouracil decreases expression ISO RGD:735172 6480464 Propylthiouracil results in decreased expression of RAB15 mRNA CTD PMID:24780913 ammonium chloride affects expression ISO RGD:735172 6480464 Ammonium Chloride affects the expression of RAB15 mRNA CTD PMID:16483693 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of RAB15 mRNA CTD PMID:22521957 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of RAB15 mRNA CTD PMID:20458559 benzo[a]pyrene decreases expression ISO RGD:735172 6480464 Benzo(a)pyrene results in decreased expression of RAB15 mRNA CTD PMID:21839799 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of RAB15 mRNA CTD PMID:22316170 bisphenol A increases expression ISO RGD:735172 6480464 bisphenol A results in increased expression of RAB15 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:735172 6480464 bisphenol A results in increased methylation of RAB15 gene CTD PMID:28505145 C60 fullerene increases expression ISO RGD:735172 6480464 fullerene C60 results in increased expression of RAB15 mRNA CTD PMID:19167457 choline multiple interactions ISO RGD:1332034 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAB15 mRNA CTD PMID:20938992 cocaine affects expression ISO RGD:735172 6480464 Cocaine affects the expression of RAB15 mRNA CTD PMID:20187946 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of RAB15 mRNA CTD PMID:20106945 , PMID:25562108 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of RAB15 mRNA CTD PMID:20458559 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of RAB15 mRNA CTD PMID:22521957 dichlorine increases expression ISO RGD:735172 6480464 Chlorine results in increased expression of RAB15 mRNA CTD PMID:18636392 dichlorine multiple interactions ISO RGD:735172 6480464 [Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA CTD PMID:18636392 diuron decreases expression ISO RGD:735172 6480464 Diuron results in decreased expression of RAB15 mRNA CTD PMID:21551480 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB15 mRNA CTD PMID:27188386 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of RAB15 mRNA CTD PMID:29803840 endosulfan decreases expression ISO RGD:735172 6480464 Endosulfan results in decreased expression of RAB15 mRNA CTD PMID:29391264 ethanol multiple interactions ISO RGD:1332034 6480464 Ethanol affects the expression of and affects the splicing of RAB15 mRNA CTD PMID:30319688 ferric oxide increases expression ISO RGD:1332034 6480464 ferric oxide analog results in increased expression of RAB15 mRNA CTD PMID:25086211 folic acid multiple interactions ISO RGD:1332034 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAB15 mRNA CTD PMID:20938992 furan increases expression ISO RGD:735172 6480464 furan results in increased expression of RAB15 mRNA CTD PMID:27387713 genistein multiple interactions ISO RGD:735172 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of RAB15 mRNA CTD PMID:21782745 genistein increases expression ISO RGD:735172 6480464 Genistein results in increased expression of RAB15 mRNA CTD PMID:21782745 L-methionine multiple interactions ISO RGD:1332034 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAB15 mRNA CTD PMID:20938992 lead(0) affects expression EXP 6480464 Lead affects the expression of RAB15 mRNA CTD PMID:28903495 lead(2+) affects expression EXP 6480464 Lead affects the expression of RAB15 mRNA CTD PMID:28903495 methoxychlor increases expression ISO RGD:735172 6480464 Methoxychlor results in increased expression of RAB15 mRNA CTD PMID:21782745 methoxychlor multiple interactions ISO RGD:735172 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of RAB15 mRNA CTD PMID:21782745 ozone multiple interactions ISO RGD:735172 6480464 [Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA CTD PMID:18636392 phenethyl isothiocyanate affects binding EXP 6480464 RAB15 protein binds to phenethyl isothiocyanate CTD PMID:21838287 progesterone multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of RAB15 mRNA CTD PMID:17404688 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of RAB15 mRNA CTD PMID:21540246 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB15 mRNA CTD PMID:27188386 silver atom decreases expression ISO RGD:1332034 6480464 Silver results in decreased expression of RAB15 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1332034 6480464 Silver results in decreased expression of RAB15 mRNA CTD PMID:27131904 tetrachloromethane affects expression ISO RGD:1332034 6480464 Carbon Tetrachloride affects the expression of RAB15 mRNA CTD PMID:17484886 trichloroethene increases methylation ISO RGD:735172 6480464 Trichloroethylene results in increased methylation of RAB15 gene CTD PMID:27618143 tris(2-butoxyethyl) phosphate affects expression EXP 6480464 tris(2-butoxyethyl) phosphate affects the expression of RAB15 mRNA CTD PMID:29024780 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of RAB15 gene CTD PMID:29154799 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB15 mRNA CTD PMID:27188386 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of RAB15 mRNA CTD PMID:19101580 more ... vinclozolin affects expression ISO RGD:735172 6480464 vinclozolin affects the expression of RAB15 mRNA CTD PMID:19015723 
Gene Ontology Annotations
