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Gene: ELF4 (E74 like ETS transcription factor 4) Homo sapiens
Symbol: ELF4
Name: E74 like ETS transcription factor 4
Description: The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E74-like factor 4 (ets domain transcription factor); ELFR; ETS-related transcription factor Elf-4; MEF; myeloid Elf-1-like factor
Mus musculus (house mouse) : Elf4 (E74-like factor 4 (ets domain transcription factor))  MGI  Alliance
Rattus norvegicus (Norway rat) : Elf4 (E74 like ETS transcription factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elf4 (E74 like ETS transcription factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ELF4 (E74 like ETS transcription factor 4)
Canis lupus familiaris (dog) : ELF4 (E74 like ETS transcription factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elf4 (E74 like ETS transcription factor 4)
Sus scrofa (pig) : ELF4 (E74 like ETS transcription factor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X130,064,920 - 130,110,713 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X129,198,895 - 129,244,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,026,586 - 129,072,153 (-)NCBINCBI36hg18NCBI36
Build 34X128,924,439 - 128,970,001NCBI
CeleraX129,585,456 - 129,631,249 (-)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX118,596,924 - 118,641,306 (-)NCBIHuRef
CHM1_1X129,110,060 - 129,156,280 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ELF4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351734
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.