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Gene: ARL8B (ADP ribosylation factor like GTPase 8B) Homo sapiens
Symbol: ARL8B
Name: ADP ribosylation factor like GTPase 8B
Description: Exhibits purine ribonucleoside binding activity and tubulin binding activity. Involved in chromosome segregation and lysosome localization. Localizes to the cytoplasm; midbody; and spindle midzone. Colocalizes with the lysosomal membrane; INTERACTS WITH arsenous acid; benzo[a]pyrene diol epoxide I; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosylation factor like GTPase 8B; ADP-ribosylation factor-like 10C; ADP-ribosylation factor-like 8B; ADP-ribosylation factor-like protein 10C; ADP-ribosylation factor-like protein 8B; ARL10C; FLJ10702; Gie1; novel small G protein indispensable for equal chromosome segregation 1
Mus musculus (house mouse) : Arl8b (ADP-ribosylation factor-like 8B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arl8b (ADP-ribosylation factor like GTPase 8B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arl8b (ADP ribosylation factor like GTPase 8B)
Pan paniscus (bonobo/pygmy chimpanzee) : ARL8B (ADP ribosylation factor like GTPase 8B)
Canis lupus familiaris (dog) : ARL8B (ADP ribosylation factor like GTPase 8B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arl8b (ADP ribosylation factor like GTPase 8B)
Sus scrofa (pig) : ARL8B (ADP ribosylation factor like GTPase 8B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl35,122,245 - 5,180,912 (+)Ensembl
GRCh3835,122,292 - 5,180,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3735,163,930 - 5,222,601 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3635,138,930 - 5,197,601 (+)NCBINCBI36hg18NCBI36
Build 3435,138,929 - 5,197,599NCBI
Celera35,101,851 - 5,160,484 (+)NCBI
Cytogenetic Map3p26.1NCBI
HuRef35,096,488 - 5,155,029 (+)NCBIHuRef
CHM1_135,114,266 - 5,172,980 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARL8B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351870
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.