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Gene: TAZ (tafazzin) Homo sapiens
Symbol: TAZ
Name: tafazzin
Description: This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BTHS; CMD3A; EFE; EFE2; FLJ27390; G4.5; LVNCX; Taz1; transcriptional coactivator with PDZ-binding motif; XAP-2
Mus musculus (house mouse) : Taz (tafazzin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Taz (tafazzin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Taz (tafazzin)
Pan paniscus (bonobo/pygmy chimpanzee) : TAZ (tafazzin)
Canis lupus familiaris (dog) : TAZ (tafazzin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Taz (tafazzin)
Sus scrofa (pig) : TAZ (tafazzin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: TAZ (GeneID 6901) and WWTR1 (GeneID 25937) loci share the TAZ symbol/alias in common. TAZ is a widely used alternative name for the transcriptional coactivator with PDZ-binding motif (WWTR1) conflicting with the official symbol for tafazzin (TAZ). [19 Jun 2012]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,411,518 - 154,421,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,639,877 - 153,650,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,293,071 - 153,303,259 (+)NCBINCBI36hg18NCBI36
Build 34X153,160,723 - 153,170,908NCBI
CeleraX153,800,935 - 153,811,119 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,217,267 - 142,227,597 (+)NCBIHuRef
CHM1_1X153,551,502 - 153,561,710 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TAZ
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1351979
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.