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Gene: CBX3 (chromobox 3) Homo sapiens
Symbol: CBX3
Name: chromobox 3
Description: Exhibits histone methyltransferase binding activity; identical protein binding activity; and protein domain specific binding activity. Involved in cellular response to DNA damage stimulus and negative regulation of transcription, DNA-templated. Localizes to the chromosome and spindle. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chromobox homolog 3 (HP1 gamma homolog, Drosophila); chromobox protein homolog 3; HECH; heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HP1 gamma homolog; HP1-GAMMA; HP1Hs-gamma; modifier 2 protein
Mus musculus (house mouse) : Cbx3 (chromobox 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cbx3 (chromobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cbx3 (chromobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CBX3 (chromobox 3)
Canis lupus familiaris (dog) : CBX3 (chromobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cbx3 (chromobox 3)
Sus scrofa (pig) : CBX3 (chromobox 3)
Chlorocebus sabaeus (green monkey) : CBX3 (chromobox 3)
Heterocephalus glaber (naked mole-rat) : Cbx3 (chromobox 3)
more info ...
Related Pseudogenes: CBX3P1   CBX3P2   CBX3P3   CBX3P4   CBX3P5   CBX3P6   CBX3P7   CBX3P8   CBX3P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl726,201,162 - 26,213,607 (+)Ensembl
GRCh38726,201,443 - 26,213,607 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37726,240,831 - 26,253,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36726,207,624 - 26,219,501 (+)NCBINCBI36hg18NCBI36
Build 34726,014,563 - 26,026,216NCBI
Celera726,230,084 - 26,241,954 (+)NCBI
Cytogenetic Map7p15.2NCBI
HuRef726,122,745 - 26,135,135 (+)NCBIHuRef
CHM1_1726,234,045 - 26,252,803 (+)NCBICHM1_1
CRA_TCAGchr7v2726,291,980 - 26,304,374 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CBX3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352044
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.