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Gene: CRLF2 (cytokine receptor like factor 2) Homo sapiens
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Symbol: CRLF2
Name: cytokine receptor like factor 2
Description: Exhibits cytokine receptor activity. Involved in several processes, including positive regulation of interleukin-5 secretion; positive regulation of mast cell activation; and positive regulation of receptor signaling pathway via STAT. Predicted to localize to the external side of plasma membrane and receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CRL2; CRLF2Y; cytokine receptor CRL2 precusor; cytokine receptor-like 2; cytokine receptor-like factor 2; IL-XR; P2RY8/CRLF2 fusion; thymic stromal lymphopoietin protein receptor; thymic stromal lymphopoietin receptor; thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR
Orthologs:
Mus musculus (house mouse) : Crlf2 (cytokine receptor-like factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Crlf2 (cytokine receptor-like factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crlf2 (cytokine receptor like factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CRLF2 (cytokine receptor like factor 2)
Canis lupus familiaris (dog) : CRLF2 (cytokine receptor like factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crlf2 (cytokine receptor like factor 2)
Sus scrofa (pig) : CRLF2 (cytokine receptor-like factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y1,190,437 - 1,212,762 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38X1,190,437 - 1,212,762 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X1,314,869 - 1,331,529 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37Y1,264,869 - 1,281,529 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X1,274,894 - 1,291,529 (-)NCBINCBI36hg18NCBI36
Build 36Y1,274,894 - 1,291,529 (-)NCBINCBI36hg18NCBI36
CeleraX5,605,262 - 5,605,961 (-)NCBI
Cytogenetic MapXp22.33 and Yp11.2NCBI
CHM1_1X1,345,456 - 1,361,668 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CRLF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352132
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.