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Gene: RAP1A (RAP1A, member of RAS oncogene family) Homo sapiens
Symbol: RAP1A
Name: RAP1A, member of RAS oncogene family
Description: Predicted to have GTPase activity; Rap guanyl-nucleotide exchange factor activity; and purine ribonucleoside binding activity. Involved in several processes, including Rap protein signal transduction; cellular response to cAMP; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Localizes to the glutamatergic synapse and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C21KG; G-22K; GTP-binding protein smg p21A; KREV-1; KREV1; RAP1; Ras-related protein Krev-1; ras-related protein Rap-1A; RAS-related protein RAP1A; SMGP21
Mus musculus (house mouse) : Rap1a (RAS-related protein 1a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rap1a (RAP1A, member of RAS oncogene family)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rap1a (RAP1A, member of RAS oncogene family)
Pan paniscus (bonobo/pygmy chimpanzee) : RAP1A (RAP1A, member of RAS oncogene family)
Canis lupus familiaris (dog) : RAP1A (RAP1A, member of RAS oncogene family)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rap1a (RAP1A, member of RAS oncogene family)
Sus scrofa (pig) : RAP1A (RAP1A, member of RAS oncogene family)
Chlorocebus sabaeus (African green monkey) : RAP1A (RAP1A, member of RAS oncogene family)
Heterocephalus glaber (naked mole-rat) : Rap1a (RAP1A, member of RAS oncogene family)
more info ...
Related Pseudogenes: RAP1AP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1111,542,218 - 111,716,691 (+)EnsemblGRCh38hg38GRCh38
GRCh381111,542,009 - 111,716,695 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371112,162,405 - 112,256,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,963,928 - 112,057,624 (+)NCBINCBI36hg18NCBI36
Build 341111,874,446 - 111,968,142NCBI
Celera1110,480,558 - 110,502,712 (+)NCBI
Cytogenetic Map1p13.2NCBI
HuRef1110,033,768 - 110,127,466 (+)NCBIHuRef
CHM1_11112,277,395 - 112,374,298 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RAP1A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352228
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.