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Gene: NUDT10 (nudix hydrolase 10) Homo sapiens
Symbol: NUDT10
Name: nudix hydrolase 10
Description: This gene is a member of the nudix (nucleoside diphosphate linked moiety X)-type motif containing family. The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of intracellular trafficking. In some populations putative prostate cancer susceptibility alleles have been identified for this gene. Alternatively spliced transcript variants, which differ only in the 5' UTR, have been found for this gene. [provided by RefSeq, Feb 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APS2; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; diadenosine hexaphosphate hydrolase (AMP-forming); diphosphoinositol polyphosphate phosphohydrolase 3-alpha; diphosphoinositol polyphosphate phosphohydrolase type 3 alpha; DIPP-3-alpha; DIPP3-alpha; DIPP3a; hAps2; hDIPP3alpha; nucleoside diphosphate-linked moiety X motif 10; nudix (nucleoside diphosphate linked moiety X)-type motif 10; nudix motif 10
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X51,332,231 - 51,337,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X51,075,083 - 51,080,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X51,091,823 - 51,097,117 (+)NCBINCBI36hg18NCBI36
Build 34X50,908,118 - 50,913,411NCBI
CeleraX55,118,909 - 55,124,202 (+)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX48,516,471 - 48,521,742 (+)NCBIHuRef
CHM1_1X51,154,988 - 51,160,299 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NUDT10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352246
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.