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Gene: NGF (nerve growth factor) Homo sapiens
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Symbol: NGF
Name: nerve growth factor
CRRD ID: 1352304
Description: Exhibits peptidase regulator activity and signaling receptor binding activity. Involved in several processes, including extrinsic apoptotic signaling pathway via death domain receptors; neuron apoptotic process; and positive regulation of macromolecule metabolic process. Predicted to localize to several cellular components, including dendrite; neuron projection terminus; and synaptic vesicle. Implicated in IgA glomerulonephritis; asthma; end stage renal disease; hereditary sensory and autonomic neuropathy type 5; and interstitial cystitis. Biomarker of several diseases, including artery disease (multiple); interstitial cystitis; lung disease (multiple); neurogenic bladder; and obstructive sleep apnea.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-nerve growth factor; Beta-NGF; HSAN5; MGC161426; MGC161428; nerve growth factor (beta polypeptide); nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGFB; pro-nerve growth factor long
Orthologs:
Mus musculus (house mouse) : Ngf (nerve growth factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ngf (nerve growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngf (nerve growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGF (nerve growth factor)
Canis lupus familiaris (dog) : NGF (nerve growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngf (nerve growth factor)
Sus scrofa (pig) : NGF (nerve growth factor)
Chlorocebus sabaeus (African green monkey) : NGF (nerve growth factor)
Heterocephalus glaber (naked mole-rat) : Ngf (nerve growth factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1115,285,917 - 115,338,249 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1115,285,917 - 115,338,256 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1115,285,918 - 115,338,236 (-)EnsemblGRCh38hg38GRCh38
GRCh381115,285,915 - 115,338,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371115,828,537 - 115,880,857 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361115,630,060 - 115,682,380 (-)NCBINCBI36hg18NCBI36
Build 341115,540,580 - 115,592,899NCBI
Celera1114,057,456 - 114,109,776 (-)NCBI
Cytogenetic Map1p13.2NCBI
HuRef1113,686,915 - 113,739,240 (-)NCBIHuRef
CHM1_11115,943,440 - 115,995,752 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NGF
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352304
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.