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Gene: USP10 (ubiquitin specific peptidase 10) Homo sapiens
Symbol: USP10
Name: ubiquitin specific peptidase 10
Description: Exhibits cysteine-type peptidase activity; ion channel binding activity; and p53 binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to interleukin-1; and negative regulation of I-kappaB kinase/NF-kappaB signaling. Localizes to several cellular components, including the cytosol; early endosome; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deubiquitinating enzyme 10; KIAA0190; MGC2621; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10; UBPO
Mus musculus (house mouse) : Usp10 (ubiquitin specific peptidase 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp10 (ubiquitin specific peptidase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp10 (ubiquitin specific peptidase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : USP10 (ubiquitin specific peptidase 10)
Canis lupus familiaris (dog) : USP10 (ubiquitin specific peptidase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp10 (ubiquitin specific peptidase 10)
Sus scrofa (pig) : USP10 (ubiquitin specific peptidase 10)
more info ...
Related Pseudogenes: USP10P1   USP10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381684,699,977 - 84,779,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371684,733,555 - 84,813,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,291,056 - 83,371,029 (+)NCBINCBI36hg18NCBI36
Build 341683,291,084 - 83,370,670NCBI
Celera1669,035,743 - 69,115,795 (+)NCBI
Cytogenetic Map16q24.1NCBI
HuRef1670,486,450 - 70,566,405 (+)NCBIHuRef
CHM1_11686,145,099 - 86,225,097 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on USP10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352341
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.