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Gene: USP10 (ubiquitin specific peptidase 10) Homo sapiens
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Symbol: USP10
Name: ubiquitin specific peptidase 10
Description: Exhibits cysteine-type peptidase activity; ion channel binding activity; and p53 binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to interleukin-1; and negative regulation of I-kappaB kinase/NF-kappaB signaling. Localizes to several cellular components, including the cytosol; early endosome; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deubiquitinating enzyme 10; KIAA0190; MGC2621; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10; UBPO
Orthologs:
Mus musculus (house mouse) : Usp10 (ubiquitin specific peptidase 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp10 (ubiquitin specific peptidase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp10 (ubiquitin specific peptidase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : USP10 (ubiquitin specific peptidase 10)
Canis lupus familiaris (dog) : USP10 (ubiquitin specific peptidase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp10 (ubiquitin specific peptidase 10)
Sus scrofa (pig) : USP10 (ubiquitin specific peptidase 10)
more info ...
Related Pseudogenes: USP10P1   USP10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381684,699,977 - 84,779,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371684,733,555 - 84,813,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,291,056 - 83,371,029 (+)NCBINCBI36hg18NCBI36
Build 341683,291,084 - 83,370,670NCBI
Celera1669,035,743 - 69,115,795 (+)NCBI
Cytogenetic Map16q24.1NCBI
HuRef1670,486,450 - 70,566,405 (+)NCBIHuRef
CHM1_11686,145,099 - 86,225,097 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on USP10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352341
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.