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Gene: CLDN2 (claudin 2) Homo sapiens
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Symbol: CLDN2
Name: claudin 2
Description: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: claudin-2; SP82
Orthologs:
Mus musculus (house mouse) : Cldn2 (claudin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cldn2 (claudin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn2 (claudin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN2 (claudin 2)
Canis lupus familiaris (dog) : CLDN2 (claudin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn2 (claudin 2)
Sus scrofa (pig) : CLDN2 (claudin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X106,900,164 - 106,930,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X106,143,394 - 106,174,091 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,050,290 - 106,060,747 (+)NCBINCBI36hg18NCBI36
Build 34X105,969,778 - 105,980,236NCBI
CeleraX106,614,779 - 106,645,477 (+)NCBI
Cytogenetic MapXq22.3NCBI
HuRefX95,771,755 - 95,802,061 (+)NCBIHuRef
CHM1_1X106,054,200 - 106,084,897 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CLDN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352349
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.