Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DEGS2 (delta 4-desaturase, sphingolipid 2) Homo sapiens
Analyze
Symbol: DEGS2
Name: delta 4-desaturase, sphingolipid 2
Description: Predicted to have sphingolipid delta-4 desaturase activity and sphingosine hydroxylase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to the endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C14orf66; degenerative spermatocyte homolog 2, lipid desaturase; delta(4)-desaturase, sphingolipid 2; DES2; dihydroceramide desaturase 2; FADS8; sphingolipid 4-desaturase; sphingolipid C4-hydroxylase/delta 4-desaturase; sphingolipid C4-monooxygenase; sphingolipid delta 4 desaturase/C-4 hydroxylase; sphingolipid delta(4)-desaturase 2; sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
Orthologs:
Mus musculus (house mouse) : Degs2 (delta(4)-desaturase, sphingolipid 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Degs2 (delta(4)-desaturase, sphingolipid 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Degs2 (delta 4-desaturase, sphingolipid 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DEGS2 (delta 4-desaturase, sphingolipid 2)
Canis lupus familiaris (dog) : DEGS2 (delta 4-desaturase, sphingolipid 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Degs2 (delta 4-desaturase, sphingolipid 2)
Sus scrofa (pig) : DEGS2 (delta 4-desaturase, sphingolipid 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl14100,143,957 - 100,159,645 (-)Ensembl
GRCh3814100,143,957 - 100,166,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714100,612,753 - 100,626,012 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361499,682,509 - 99,695,712 (-)NCBINCBI36hg18NCBI36
Build 341499,682,509 - 99,695,712NCBI
Celera1480,667,585 - 80,680,837 (-)NCBI
Cytogenetic Map14q32.2NCBI
HuRef1480,794,810 - 80,808,042 (-)NCBIHuRef
CHM1_114100,550,475 - 100,563,702 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DEGS2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352357
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.