Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: BCL2L2 (BCL2 like 2) Homo sapiens
Analyze
Symbol: BCL2L2
Name: BCL2 like 2
Description: Exhibits disordered domain specific binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in negative regulation of apoptotic process. Localizes to the Bcl-2 family protein complex. Implicated in transient cerebral ischemia. Biomarker of Alzheimer's disease; Burkitt lymphoma; colorectal adenocarcinoma; diffuse large B-cell lymphoma; and multiple sclerosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apoptosis regulator BCL-W; bcl-2-like protein 2; BCL-W; BCL2-L-2; BCL2-like 2 protein; BCLW; KIAA0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
Orthologs:
Mus musculus (house mouse) : Bcl2l2 (BCL2-like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bcl2l2 (Bcl2-like 2)  Alliance
Canis lupus familiaris (dog) : BCL2L2 (BCL2 like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl2l2 (BCL2 like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,306,762 - 23,311,759 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371423,775,971 - 23,790,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,845,852 - 22,850,808 (+)NCBINCBI36hg18NCBI36
Build 341422,845,875 - 22,850,798NCBI
Celera143,638,729 - 3,643,685 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef143,892,647 - 3,897,644 (+)NCBIHuRef
CHM1_11423,774,641 - 23,779,638 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BCL2L2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352362
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.