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Gene: NOL3 (nucleolar protein 3) Homo sapiens
Symbol: NOL3
Name: nucleolar protein 3
Description: Exhibits several functions, including caspase binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and identical protein binding activity. Involved in several processes, including mRNA splice site selection; negative regulation of apoptotic process; and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Localizes to the cytoplasm and nucleolus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARC; CARD2; FCM; FLJ35304; muscle-enriched cytoplasmic protein; MYC; MYOCL1; MYP; NOP; NOP30; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa
Mus musculus (house mouse) : Nol3 (nucleolar protein 3 (apoptosis repressor with CARD domain))  MGI  Alliance
Rattus norvegicus (Norway rat) : Nol3 (nucleolar protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nol3 (nucleolar protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NOL3 (nucleolar protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nol3 (nucleolar protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381667,170,497 - 67,175,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371667,204,400 - 67,209,640 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,765,371 - 65,767,127 (+)NCBINCBI36hg18NCBI36
Build 341665,765,370 - 65,767,125NCBI
Celera1651,712,649 - 51,717,887 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1653,077,589 - 53,082,828 (+)NCBIHuRef
CHM1_11668,611,732 - 68,616,967 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NOL3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352407
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.