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Gene: IL6 (interleukin 6) Homo sapiens
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Symbol: IL6
Name: interleukin 6
Description: Exhibits cytokine activity; growth factor activity; and interleukin-6 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of cytokine production; and positive regulation of macromolecule metabolic process. Localizes to the extracellular space and interleukin-6 receptor complex. Implicated in several diseases, including autoimmune hypersensitivity disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Biomarker of several diseases, including autoimmune hypersensitivity disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); hematologic cancer (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B cell stimulatory factor-2; B-cell differentiation factor; B-cell stimulatory factor 2; BSF-2; BSF2; CDF; CTL differentiation factor; HGF; HSF; hybridoma growth factor; IFN-beta-2; IFNB2; IL-6; interferon beta-2; interferon, beta 2; interleukin BSF-2; interleukin-6
Orthologs:
Mus musculus (house mouse) : Il6 (interleukin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il6 (interleukin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il6 (interleukin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : IL6 (interleukin 6)
Canis lupus familiaris (dog) : IL6 (interleukin 6)
Sus scrofa (pig) : IL6 (interleukin 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38722,725,889 - 22,732,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37722,766,766 - 22,771,621 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36722,733,343 - 22,738,145 (+)NCBINCBI36hg18NCBI36
Build 34722,540,059 - 22,544,856NCBI
Celera722,752,396 - 22,757,251 (+)NCBI
Cytogenetic Map7p15.3NCBI
HuRef722,649,846 - 22,654,701 (+)NCBIHuRef
CHM1_1722,767,664 - 22,772,524 (+)NCBICHM1_1
CRA_TCAGchr7v2722,817,875 - 22,822,730 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model