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Gene: ZP3 (zona pellucida glycoprotein 3) Homo sapiens
Symbol: ZP3
Name: zona pellucida glycoprotein 3
CRRD ID: 1352592
Description: Exhibits acrosin binding activity; carbohydrate binding activity; and identical protein binding activity. Involved in several processes, including binding activity of sperm to zona pellucida; negative regulation of binding activity of sperm to zona pellucida; and positive regulation of acrosomal vesicle exocytosis. Localizes to collagen-containing extracellular matrix; egg coat; and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OOMD3; sperm receptor; zona pellucida glycoprotein 3 (sperm receptor); zona pellucida glycoprotein 3A (sperm receptor); zona pellucida glycoprotein 3B; zona pellucida glycoprotein ZP3; zona pellucida protein C; zona pellucida sperm-binding protein 3; Zp-3; ZP3A; ZP3A/ZP3B; ZP3B; ZPC
Mus musculus (house mouse) : Zp3 (zona pellucida glycoprotein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zp3 (zona pellucida glycoprotein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zp3 (zona pellucida glycoprotein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ZP3 (zona pellucida glycoprotein 3)
Canis lupus familiaris (dog) : ZP3 (zona pellucida glycoprotein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zp3 (zona pellucida glycoprotein 3)
Sus scrofa (pig) : ZP3 (zona pellucida glycoprotein 3)
Chlorocebus sabaeus (African green monkey) : ZP3 (zona pellucida glycoprotein 3)
Heterocephalus glaber (naked mole-rat) : Zp3 (zona pellucida glycoprotein 3)
more info ...
Related Pseudogenes: ZP3P1   ZP3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl776,397,518 - 76,442,071 (+)EnsemblGRCh38hg38GRCh38
GRCh38776,397,522 - 76,442,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37776,026,841 - 76,071,388 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,864,804 - 75,909,324 (+)NCBINCBI36hg18NCBI36
Build 34775,671,518 - 75,716,038NCBI
Celera770,895,359 - 70,931,910 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef771,113,333 - 71,158,989 (+)NCBIHuRef
CHM1_1775,957,109 - 76,001,648 (+)NCBICHM1_1
CRA_TCAGchr7v2775,359,905 - 75,404,452 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352592
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.