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Gene: PKN2 (protein kinase N2) Homo sapiens
Symbol: PKN2
Name: protein kinase N2
Description: Exhibits RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including apical junction assembly; positive regulation of cell cycle; and positive regulation of viral genome replication. Localizes to several cellular components, including cleavage furrow; cytoskeleton; and midbody; INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cardiolipin-activated protein kinase Pak2; MGC150606; MGC71074; Pak-2; PAK2; PKN gamma; PRK2; PRKCL2; PRO2042; protein kinase C-like 2; protein-kinase C-related kinase 2; serine/threonine-protein kinase N2; STK7
Mus musculus (house mouse) : Pkn2 (protein kinase N2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pkn2 (protein kinase N2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pkn2 (protein kinase N2)
Pan paniscus (bonobo/pygmy chimpanzee) : PKN2 (protein kinase N2)
Canis lupus familiaris (dog) : PKN2 (protein kinase N2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pkn2 (protein kinase N2)
Sus scrofa (pig) : PKN2 (protein kinase N2)
Chlorocebus sabaeus (African green monkey) : PKN2 (protein kinase N2)
Heterocephalus glaber (naked mole-rat) : Pkn2 (protein kinase N2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl188,684,222 - 88,836,255 (+)EnsemblGRCh38hg38GRCh38
GRCh38188,684,144 - 88,836,255 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37189,149,876 - 89,301,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36188,922,510 - 89,074,526 (+)NCBINCBI36hg18NCBI36
Build 34188,862,276 - 89,011,443NCBI
Celera187,395,729 - 87,547,728 (+)NCBI
Cytogenetic Map1p22.2NCBI
HuRef187,267,203 - 87,419,414 (+)NCBIHuRef
CHM1_1189,264,924 - 89,416,992 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PKN2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352598
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.