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Gene: LHX3 (LIM homeobox 3) Homo sapiens
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Symbol: LHX3
Name: LIM homeobox 3
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and sequence-specific DNA binding activity. Involved in inner ear development and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in panhypopituitarism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPHD3; DKFZp762A2013; LIM homeobox protein 3; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3; LIM3; M2-LHX3
Orthologs:
Mus musculus (house mouse) : Lhx3 (LIM homeobox protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lhx3 (LIM homeobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhx3 (LIM homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LHX3 (LIM homeobox 3)
Canis lupus familiaris (dog) : LHX3 (LIM homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhx3 (LIM homeobox 3)
Sus scrofa (pig) : LHX3 (LIM homeobox 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,196,250 - 136,205,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,088,096 - 139,096,955 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,227,917 - 138,236,776 (-)NCBINCBI36hg18NCBI36
Build 349136,314,040 - 136,322,900NCBI
Celera9109,606,466 - 109,615,325 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,552,281 - 108,560,958 (-)NCBIHuRef
CHM1_19139,236,859 - 139,245,738 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LHX3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352685
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.