Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LHX3 (LIM homeobox 3) Homo sapiens
Symbol: LHX3
Name: LIM homeobox 3
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and sequence-specific DNA binding activity. Involved in inner ear development and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in panhypopituitarism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPHD3; DKFZp762A2013; LIM homeobox protein 3; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3; LIM3; M2-LHX3
Mus musculus (house mouse) : Lhx3 (LIM homeobox protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lhx3 (LIM homeobox 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lhx3 (LIM homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LHX3 (LIM homeobox 3)
Canis lupus familiaris (dog) : LHX3 (LIM homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lhx3 (LIM homeobox 3)
Sus scrofa (pig) : LHX3 (LIM homeobox 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389136,196,250 - 136,205,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,088,096 - 139,096,955 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,227,917 - 138,236,776 (-)NCBINCBI36hg18NCBI36
Build 349136,314,040 - 136,322,900NCBI
Celera9109,606,466 - 109,615,325 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,552,281 - 108,560,958 (-)NCBIHuRef
CHM1_19139,236,859 - 139,245,738 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LHX3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352685
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.