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Gene: IL1R2 (interleukin 1 receptor type 2) Homo sapiens
Symbol: IL1R2
Name: interleukin 1 receptor type 2
Description: Predicted to have interleukin-1 binding activity and interleukin-1 receptor activity. Predicted to be involved in immune response and interleukin-1-mediated signaling pathway. Predicted to localize to the plasma membrane. Implicated in aggressive periodontitis. Biomarker of aggressive periodontitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL-1R-beta; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; interleukin-1 receptor beta; interleukin-1 receptor type 2; interleukin-1 receptor type II; MGC47725; type II interleukin-1 receptor, beta
Mus musculus (house mouse) : Il1r2 (interleukin 1 receptor, type II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il1r2 (interleukin 1 receptor type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1r2 (interleukin 1 receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IL1R2 (interleukin 1 receptor type 2)
Canis lupus familiaris (dog) : IL1R2 (interleukin 1 receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1r2 (interleukin 1 receptor type 2)
Sus scrofa (pig) : IL1R2 (interleukin 1 receptor type 2)
Chlorocebus sabaeus (African green monkey) : IL1R2 (interleukin 1 receptor type 2)
Heterocephalus glaber (naked mole-rat) : Il1r2 (interleukin 1 receptor type 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2101,991,960 - 102,028,544 (+)Ensembl
GRCh382101,991,805 - 102,028,544 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372102,608,306 - 102,644,885 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362101,974,738 - 102,011,317 (+)NCBINCBI36hg18NCBI36
Build 342102,073,976 - 102,103,400NCBI
Celera296,809,517 - 96,846,098 (+)NCBI
Cytogenetic Map2q11.2NCBI
HuRef296,372,116 - 96,408,738 (+)NCBIHuRef
CHM1_12102,612,636 - 102,649,275 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL1R2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352690
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.