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Gene: TTF1 (transcription termination factor 1) Homo sapiens
Symbol: TTF1
Name: transcription termination factor 1
Description: Predicted to have chromatin binding activity. Predicted to be involved in termination of RNA polymerase I transcription. Localizes to the cytosol; nuclear lumen; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: RNA polymerase I termination factor; transcription termination factor I; transcription termination factor, RNA polymerase I; TTF-1; TTF-I
Mus musculus (house mouse) : Ttf1 (transcription termination factor, RNA polymerase I)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttf1 (transcription termination factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttf1 (transcription termination factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TTF1 (transcription termination factor 1)
Canis lupus familiaris (dog) : TTF1 (transcription termination factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttf1 (transcription termination factor 1)
Sus scrofa (pig) : TTF1 (transcription termination factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: TTF1 (GeneID 7270) and NKX2-1 (GeneID 7080) loci share the TTF1 symbol/alias in common. TTF1 is a widely used alternative name for thyroid transcription factor 1 (NKX2-1) conflicting with the official symbol for transcription termination factor, RNA polymerase I (TTF1). [13 Feb 2013]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389132,375,548 - 132,406,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379135,250,935 - 135,282,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,240,756 - 134,272,042 (-)NCBINCBI36hg18NCBI36
Build 349132,280,492 - 132,311,775NCBI
Celera9105,792,754 - 105,824,048 (-)NCBI
Cytogenetic Map9q34.13NCBI
HuRef9104,744,257 - 104,775,555 (-)NCBIHuRef
CHM1_19135,400,954 - 135,432,252 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TTF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352742
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.