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Gene: MCM6 (minichromosome maintenance complex component 6) Homo sapiens
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Symbol: MCM6
Name: minichromosome maintenance complex component 6
Description: Exhibits identical protein binding activity. Contributes to DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and double-strand break repair via break-induced replication. Localizes to the MCM complex and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA replication licensing factor MCM6; MCG40308; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); mcm6 minichromosome maintenance deficient 6 (mis5 homolog, s. pombe) (s. cerevisiae); minichromosome maintenance deficient (mis5, S. pombe) 6; minichromosome maintenance deficient 6 homolog; Mis5; MIS5 homolog; P105MCM
Orthologs:
Mus musculus (house mouse) : Mcm6 (minichromosome maintenance complex component 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mcm6 (minichromosome maintenance complex component 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcm6 (minichromosome maintenance complex component 6)
Pan paniscus (bonobo/pygmy chimpanzee) : MCM6 (minichromosome maintenance complex component 6)
Canis lupus familiaris (dog) : MCM6 (minichromosome maintenance complex component 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcm6 (minichromosome maintenance complex component 6)
Sus scrofa (pig) : MCM6 (minichromosome maintenance complex component 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,839,626 - 135,876,443 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372136,597,196 - 136,634,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,313,666 - 136,350,481 (-)NCBINCBI36hg18NCBI36
Build 342136,430,929 - 136,467,743NCBI
Celera2130,307,953 - 130,344,734 (-)NCBI
Cytogenetic Map2q21.3NCBI
HuRef2128,590,433 - 128,627,241 (-)NCBIHuRef
CHM1_12136,602,596 - 136,639,440 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MCM6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352854
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.