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Gene: MCM6 (minichromosome maintenance complex component 6) Homo sapiens
Symbol: MCM6
Name: minichromosome maintenance complex component 6
Description: Exhibits identical protein binding activity. Contributes to DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and double-strand break repair via break-induced replication. Localizes to the MCM complex and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA replication licensing factor MCM6; MCG40308; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); mcm6 minichromosome maintenance deficient 6 (mis5 homolog, s. pombe) (s. cerevisiae); minichromosome maintenance deficient (mis5, S. pombe) 6; minichromosome maintenance deficient 6 homolog; Mis5; MIS5 homolog; P105MCM
Mus musculus (house mouse) : Mcm6 (minichromosome maintenance complex component 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mcm6 (minichromosome maintenance complex component 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcm6 (minichromosome maintenance complex component 6)
Pan paniscus (bonobo/pygmy chimpanzee) : MCM6 (minichromosome maintenance complex component 6)
Canis lupus familiaris (dog) : MCM6 (minichromosome maintenance complex component 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcm6 (minichromosome maintenance complex component 6)
Sus scrofa (pig) : MCM6 (minichromosome maintenance complex component 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382135,839,626 - 135,876,443 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372136,597,196 - 136,634,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,313,666 - 136,350,481 (-)NCBINCBI36hg18NCBI36
Build 342136,430,929 - 136,467,743NCBI
Celera2130,307,953 - 130,344,734 (-)NCBI
Cytogenetic Map2q21.3NCBI
HuRef2128,590,433 - 128,627,241 (-)NCBIHuRef
CHM1_12136,602,596 - 136,639,440 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MCM6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352854
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.