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Gene: S1PR3 (sphingosine-1-phosphate receptor 3) Homo sapiens
Symbol: S1PR3
Name: sphingosine-1-phosphate receptor 3
Description: Exhibits integrin binding activity. Involved in negative regulation of establishment of endothelial barrier. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EDG-3; EDG3; endothelial differentiation G-protein coupled receptor 3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; FLJ37523; FLJ93220; G protein-coupled receptor, endothelial differentiation gene-3; LPB3; MGC71696; S1P receptor 3; S1P receptor Edg-3; S1P receptor EDG3; S1P3; sphingosine 1-phosphate receptor 3; sphingosine 1-phosphate receptor Edg-3
Mus musculus (house mouse) : S1pr3 (sphingosine-1-phosphate receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : S1pr3 (sphingosine-1-phosphate receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr3 (sphingosine-1-phosphate receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR3 (sphingosine-1-phosphate receptor 3)
Canis lupus familiaris (dog) : S1PR3 (sphingosine-1-phosphate receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr3 (sphingosine-1-phosphate receptor 3)
Sus scrofa (pig) : S1PR3 (sphingosine-1-phosphate receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38988,991,468 - 89,005,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37991,606,324 - 91,620,070 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36990,796,182 - 90,809,745 (+)NCBINCBI36hg18NCBI36
Build 34988,835,915 - 88,849,478NCBI
Celera962,189,011 - 62,202,574 (+)NCBI
Cytogenetic Map9q22.1NCBI
HuRef961,438,768 - 61,452,511 (+)NCBIHuRef
CHM1_1991,754,483 - 91,768,224 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on S1PR3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352881
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.