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Gene: KCNJ2 (potassium inwardly rectifying channel subfamily J member 2) Homo sapiens
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Symbol: KCNJ2
Name: potassium inwardly rectifying channel subfamily J member 2
CRRD ID: 1352992
Description: Exhibits identical protein binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and voltage-gated potassium channel activity. Involved in several processes, including cardiac muscle cell action potential; potassium ion import across plasma membrane; and protein homotetramerization. Localizes to voltage-gated potassium channel complex. Implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Biomarker of atrial fibrillation.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB9; cardiac inward rectifier potassium channel; HHBIRK1; HHIRK1; hIRK1; inward rectifier K(+) channel Kir2.1; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel 2; IRK-1; IRK1; KIR2.1; LQT7; potassium channel, inwardly rectifying subfamily J member 2; potassium channel, inwardly rectifying subfamily J, member 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; SQT3
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1770,168,673 - 70,180,044 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1770,168,673 - 70,180,048 (+)EnsemblGRCh38hg38GRCh38
GRCh381770,169,532 - 70,180,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371768,164,757 - 68,176,189 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,677,271 - 65,687,780 (+)NCBINCBI36hg18NCBI36
Build 341765,677,270 - 65,687,776NCBI
Celera1764,737,556 - 64,748,065 (+)NCBI
Cytogenetic Map17q24.3NCBI
HuRef1763,551,441 - 63,561,946 (+)NCBIHuRef
CHM1_11768,231,773 - 68,242,282 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KCNJ2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1352992
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.